An Israeli series of strikes against the Iranian nuclear weapons program will only set back the Iranian nuclear weapons program one to two years since no one can take away the acquired know-how from the Iranian nuclear scientists. Therefore would it be necessary for Israel to repeat the operation every two years or so. However, with a permanent no-fly zone over Iran is it possible to instantly and intermittently crack down on any attempts to revive the Iranian nuclear weapons program after it has been strategically degraded. In addition to this would Iran effectively break up as did the former Soviet Union as a US no-fly zone would lead to armed rebellions with US air support in Iran’s ethnic periphery which hosts half of Iran’s population and Tehran would also lose most of its oil resources. This would lead to the creation of many new pro-American KRG-style regional governments de facto independent from Tehran and that would also as an important, indeed crucial humanitarian side effect enable Iran’s Median Jews to leave for Israel once the gates of Median Jewish mass Aliyah (immigration to Israel) opens. A no-fly zone is not only a humanitarian necessity for Median Jewry in Iran and for half of Iran’s population who suffer under totalitarianism, it is a strategic imperative indeed.